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Dark Spot Remover Cream

Hydroquinone Tretinoin & Mometasone Furoate Cream

Kaylite Anti Marks Cream is used to reduce the colour of skin and remove any dark spots like age spots, freckles, and other skin discolouration.

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Variation in skin tone is one of the prominent distinguishable features of human beings. Skin pigmentation in humans is variable and has evolved predominantly to regulate the penetration of light (UV levels). A direct correlation has been observed between the geographical distribution of UV radiation and skin pigmentation worldwide. Kaylite cream

Some skin tones are more susceptible to pigmentation disorders than others, especially of Asia and India. Most of these disorders are attributed to or worsened by exposure of light (UV).In a study by Hourblin across four Indian cities revealed that more than 80% of the population present skin colour diversity on the face, irrespective of age and gender. This diversity mainly results from hyper-pigmented spots, melasma and dark circles.3 These disorders can cause distress and negatively impact the quality of life of an individual. Two important hyperpigmentary disorders in India, namely, melasma and post-inflammatory yperpigmentation (PIH) will be detailed below.

Melasma: an acquired pigmentary disorder, is identified by hyperpigmented brown to greyish brown spots on the face. It occurs mainly in women (90% cases) and 10% of males of all ethnic and racial groups. In India, 20–30% of 40–65 years old women present facial melasma.3 In India high incidence of melasma in high-altitude, sun-exposed environments is also seen due to high UV exposure.

While the exact cause of melasma is unknown, exposure to UV, increased estrogen levels (observed mainly during pregnancy or use of oral contraceptives), genetics and other factors like ovarian dysfunction, thyroid and/or liver diseases are also related to it.

Postinflammatory hyperpigmentation (PIH): PIH, an acquired disorder, occurs as a result of an inflammatory reaction, induced by skin diseases like acne vulgaris, atopic dermatitis, psoriasis, impetigo, lichen planus, irritant and allergic contact, photocontact-dermatitis and insect bites as well as a complication of laser therapy. In India, a majority of subjects with an acne history present pigmented post-inflammatory marks: More than 70% before 35 years old, both in women and men. This prevalence rapidly decreases with age to involve <10% of people older than 50 years.

Treatment: These disorders are challenging to treat. If hormonal factors are implicated, the use of the oral contraceptive pill or intrauterine devices should be discontinued. The other treatment options are Topical creams, Sun protection, Chemical peels, and Laser and light-based treatments.

Topical creams: Hydroquinone cream or lotion (2-8% either in a stand-alone formulation or mixed with other active ingredients) is the most widely used method to treat melasma. The higher the concentration of hydroquinone, the higher the incidence of irritant dermatitis (eczema). Hydroquinone should, therefore, be used for limited periods under the supervision of your dermatologist.

Vitamin A creams including tretinoin can be used as a stand-alone treatment or in combination with other agents. These can cause skin irritation so their use should be guided by a dermatologist and closely monitored. Ascorbic acid (vitamin C) is sometimes used in addition to other treatments such as hydroquinone.Azelaic acid (20%) has been reported to improve cases of superficial melasma.

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Combination topicals: Hydroquinone, retinoid and topical steroid combination creams are currently the best initial option for melasma management. Sun protection: Strict and absolute sun protection is essential with a broad-spectrum sunscreen (SPF 30+ or more). Sunscreens should be applied twice a day, 20 minutes prior to sun exposure. Broad brimmed hats should be worn when outdoors.

Chemical peels: Chemical peels have variable success in treating melasma. Multiple treatments are required to achieve modest benefits. They are best used in combination with topical creams.

Laser and light based treatments: Laser and light based treatments should only be used in severe cases for which the abovementioned therapies are ineffective. The risk of complications is high and multiple treatments are necessary to see a noticeable improvement.

It should be noted that even if treatments of Melasma are effective, recurrence of the conditions is common.

References:

  1. Jablonski NG, Chaplin G. J Hum Evol. 2000;39:57–106.
  2. Del Bino S, Bernerd F. Br J Dermatol. 2013;169(Suppl 3):33–40
  3. Hourblin V, Nouveau S, Roy N, de Lacharrière O. Indian J DermatolVenereolLeprol. 2014;80:395–401
  4. Ortonne JP, Passeron T, Srinivas C. In: Pigmentary Disorders, Prevention, Treatment and Cosmetics Contributions. Basic Science for Modern Cosmetic Dermatology. Srinivas C, Verschoore M, editors. New Delhi: Jaypee Brothers, Medical Publishers Pvt. Limited; 2015.
    pp. 75–90.
  5. Rendon M, Berneburg M, Arellano I, Picardo M. J Am AcadDermatol. 2006;54(5 Suppl 2):S272–81
  6. 102. Singh G, Chatterjee M, Grewal R, Verma R. Indian J Dermatol. 2013;58:107–12.

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Q1: What are the Benefits of Kaylite Cream?
Ans: Kaylite cream is beneficial in treatment of dark skin, dark spots, acne marks and hyperpigmentation of skin.

Q2: How does Kaylite Cream Work?
Ans: Hydroquinone is depigmenting agent. The combination agents in Kaylite cream act by inhibiting one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis. It also effects the formation of melanisation and degradation of melanosomes and eventually causes necrosis of the whole melanocytes. The hyperpigmented Dark spots fade rapidly than surrounding normal skin.

Q3: Is it Safe to use Kaylite cream ? What could be the possible Side-effects of Kaylite cream?
Ans: Yes, it is safe to use, There are no side effects of Kaylite cream. Avoid contact with eyes, Exposure to sunlight or UV light. Exposure to sun will cause repigmentation of bleached area. Avoid going out in sunlight during application of kaylite.

Q4: Who can use Kaylite Cream?
Ans: Both (male & female) can use. But children (12 years and under) and during pregnancy it is advised to avoid using kaylite.

Q5: For how many days, Kaylite can be used?
Ans: Kaylite cream action starts immediately and desired results are noticed within 7-10 days. It is suggested to discontinue use of kaylite cream after 30 days.

Q6: How to use Kaylite Cream?
Ans: Apply the medication to the affected areas of skin usually once a day (at night). Use sunscreen (Minimum SPF-15) during day and avoid going out in sun. Cover your face with clothes, if it is necessary to go out.

Q7: What is the MRP of Kaylite Cream?
Ans: RS.186.00

Q8 : Where will I get the Kaylite Cream ?
Ans: Kaylite is Available at www.kaylite.com.

Q9:Can Soap be used while application of Kaylite cream?
Ans: No soap should not be used while applying kaylite cream, instead use face wash and moisturising lotion.

Q10: How effective is Kaylite Cream ?
Ans. Kaylite is very effective in treatment of Dark skin, Dark spots, Acne marks and hyper pigmentation. Kaylite starts action immediately and noticeable results are seen within 7-10 days.

Uses of Kaylite cream ?
Kaylite is used in the treatment of hyperpigmentation and melasma.
How to use Kaylite cream?

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Kaylite cream works?
Kaylite belongs to the class of medications called as melanin synthesis inhibitors. It bleaches the skin by reducing the accumulation of skin pigment called melanin that causes darkening of the skin

Kaylite is a topical corticosteroid (an anti-inflammatory medicine). It works by reducing redness, itching, and swelling caused by various skin conditions.
Tretinoin Kaylite works by slowing the production of certain natural substances that can cause acne.
Expert advice for Kaylite cream

1. Use of sunscreen is a must while using Kaylite. Avoid unnecessary sun exposures and cover the treated areas with clothing. Even minimal exposure to sunlight can reverse the bleaching effect of hydroquinone.

2. Discontinue use and contact your doctor immediately if you develop allergic skin reaction or notice blue-black darkening of skin upon use of Kaylite cream.

3. Avoid direct contact of cream with your eyes. In case of direct contact, wash your eyes with water immediately and seek immediate medical attention.

4. Do not use Kaylite cream on broken, irritated or injured skin.

5. Do not use Kaylite with other creams that contain peroxides (hydrogen peroxide/benzoyl peroxide), resorcinol, phenol, or salicylic acid as it may cause unwanted side effects.

6. You may be advised by your doctor to perform a skin sensitivity test to avoid any allergic reaction

7. Use in children aged below 12 years is not recommended unless under the strict supervision of doctor.

8. Strictly for external use only.